This macro creates individual level medication of interest metrics for pregnancy analysis. More...

Detailed Description

This macro creates individual level medication of interest metrics for pregnancy analysis.

Create dataset with medical exposure during pregnancy.
- Do not count secondary cohort episodes (medical exposure) ending prior to "pre" period or beginning after the post-pregnancy period.
- Apply removal period (RemoveMOIStart/RemoveMOIEnd).
- Apply removal period (RemoveADate) to same-day dispensings when they happen on the last day of pregnancy.
If T4cohortdef2 = 01, then take the first exposure date during the pregnancy episode per MOI.
If T4cohortdef2 = 99, then take the last exposure date during the pregnancy episode per MOI.
Compute trimester use:
- Gestational week of MOI.
- When the computed gestwk is greater than the number of weeks in pregnancy episode, assign post-pregnancy values (+1, +2, +3,...).
Keep concurrent dispensings:
- Gestational week of code.
- When the computed gestwk is greater than the number of weeks in pregnancy episode, assign post-pregnancy values (+1, +2, +3,...).
Summarize _concdispensings and merge with _concepisodes.
Merge in additional variables.
Save to dplocal.

Program inputs

&COHORTFILE. (Dataset containing pregnancy codes.)
work._grouputilfile (Dataset containing defined group pregnancy and control episodes.)
work._ptsmasterlist2 (Dataset containing MOI drug codes.)

Program outputs

dplocal.&RUNID._concepi_&OUTFILE._tri (Dataset with trimester statistics for each pregnancy outcome and medical product of interest.)
work.t4_dispensings_&OUTFILE. (Dataset containing 1 row per dispensing for gestational week metrics.)

Usage

%ms_moimetrics(COHORTFILE=_PtsMasterList,
               OUTFILE=mstr_preg);

Parameters

[in]	COHORTFILE	Name of the SAS dataset that defines how Type 4 PSA/Mother-Infant cohorts will be created.
[out]	OUTFILE	Name of the output SAS dataset for Type 4 analyses.

Author: Sentinel Coordinating Center (info@.nosp@m.sent.nosp@m.inels.nosp@m.yste.nosp@m.m.org)

	QRP